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------=_NextPart_01C87D1E.E0CEF6D0 Content-Location: file:///C:/B133D201/RNA_files/slide0002.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" RNA
RNA (ribonucleic acid)
l-nucleic acid.
l-made up of repeating subunits called nucleotides. <= /div>
l
lRNA: = ribose sugar
l has uracil= as a nitrogen base
l single stranded*
l
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Types of RNA
l-three main types:
l 1.  Messenger – mRNA
l (transcript)
l 2.  Transfer – tRNA =
l 3.  Ribosomal – rRNA
l
l-other type= s: miRNA, siRNA, smRNA, shRNA, dsRNA
------=_NextPart_01C87D1E.E0CEF6D0 Content-Location: file:///C:/B133D201/RNA_files/slide0004.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" RNA
Functions of RNA…
l1. Transcription
l
l2. Translation
l
------=_NextPart_01C87D1E.E0CEF6D0 Content-Location: file:///C:/B133D201/RNA_files/slide0005.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" RNA
Transcription (nucleus)
lSteps:
l 1.  RNA Polymerase- the enzyme bonds = to promoter regions on DNA.
l 2.  DNA separates and the template st= rand is transcribed. =
l 3.  Transcription ends when the enzym= e reaches a termination signal.
------=_NextPart_01C87D1E.E0CEF6D0 Content-Location: file:///C:/B133D201/RNA_files/slide0007.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" RNA
Translation (cytoplasm)
l-The mRNA is now carrying the message that = determines what proteins are going to be made. = ;
l
lRecall= -there are 20 different amino acids that make up proteins.
l -it’s all about the sequence…
------=_NextPart_01C87D1E.E0CEF6D0 Content-Location: file:///C:/B133D201/RNA_files/slide0008.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" RNA
Translation
l-Occurs in = the cytoplasm at the ribosomes (rRNA).
l
l-Involves t= he use of start codons and stop = codons.
l
l-tRNA’= ;s bring individual amino acids to the ribosome where they begin to form long chains of amino acids.
------=_NextPart_01C87D1E.E0CEF6D0 Content-Location: file:///C:/B133D201/RNA_files/slide0009.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" RNA
l-Illustration showing translation at the ribosome.
l
l-Polypeptide is a chain of amino acids being formed.
l
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